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Literature summary extracted from

  • Pearman, A.T.; Castro-Faria-Neto, H.C.; McIntyre, T.M.; Prescott, S.M.; Stafforini, D.M.
    Characterization of human UMP-CMP kinase enzymatic activity and 5' untranslated region (2001), Life Sci., 69, 2361-2370.
    View publication on PubMed

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.4.14 Mg2+ strong requirement, maximal activity at 3 mM Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.4.14 22222
-
 x * 22222, calculation from nucleotide sequence Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.4.14 ATP + CMP Homo sapiens the enzyme is required during rapid cell growth ADP + CDP
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.4.14 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.4.14 A-549 cell lung carcinoma Homo sapiens
-
2.7.4.14 bone marrow
-
 Homo sapiens
-
2.7.4.14 Burkitt lymphoma cell
-
 Homo sapiens
-
2.7.4.14 fetus
-
 Homo sapiens
-
2.7.4.14 G-361 cell melanoma cell Homo sapiens
-
2.7.4.14 HeLa-S3 cell
-
 Homo sapiens
-
2.7.4.14 K-562 cell chronic myelogenous leukemia cell Homo sapiens
-
2.7.4.14 leukocyte
-
 Homo sapiens
-
2.7.4.14 liver
-
 Homo sapiens
-
2.7.4.14 lymph node
-
 Homo sapiens
-
2.7.4.14 macrophage
-
 Homo sapiens
-
2.7.4.14 MOLT-4 cell lymphoblastic leukemia cell Homo sapiens
-
2.7.4.14 additional information two mRNA species are expressed in all immune tissues examined, an all cases the 3.4 kb form is the more prominent RNA species Homo sapiens
-
2.7.4.14 NCI-H660 cell promyelocytic leukemia Homo sapiens
-
2.7.4.14 peripheral blood mononuclear cell
-
 Homo sapiens
-
2.7.4.14 RAJI cell
-
 Homo sapiens
-
2.7.4.14 spleen
-
 Homo sapiens
-
2.7.4.14 SW-480 cell colorectal adenocarcinoma cell Homo sapiens
-
2.7.4.14 thymus
-
 Homo sapiens
-
2.7.4.14 vermiform appendix
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.4.14 ATP + CMP
-
 Homo sapiens ADP + CDP
-
 ?
2.7.4.14 ATP + CMP the enzyme is required during rapid cell growth Homo sapiens ADP + CDP
-
 ?
2.7.4.14 ATP + UMP
-
 Homo sapiens ADP + UDP
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.4.14 ? x * 22222, calculation from nucleotide sequence Homo sapiens